Tests since 2022

Tests launched or updated since 2022:



Dominant White Test Update - A fifth allele has been added to the equine dominant white test: W13. Initially identified in a Quarter Horse X Paso Peruano cross-bred family, a study led by VGL director, Dr. Rebecca Bellone, has identified this W13 mutation in 14 American Miniature Horses and a Shetland Pony, indicating the mutation is present in multiple breeds. Horses with the W13 mutations are often reported to be all white with pink skin.


Progressive Retinal Atrophy (rcd4-PRA) - A heritable condition characterized by late onset degeneration of photoreceptor cells in the retina, which leads to blindness. This genetic variant is found in several dog breeds.

Cerebellar Degeneration-Myositis Complex (CDMC) in the Nova Scotia Duck Tolling Retriever - A heritable disorder that causes neurological signs that manifest as early as 10 weeks of age in affected Nova Scotia Duck Tolling Retrievers.

Cardiac Laminopathy (CLAM) in the Nova Scotia Duck Tolling Retriever - Discovered by Dr. Danika Bannasch at UC Davis, CLAM is a fatal heritable condition that results in dilated cardiomyopathy and sudden death in young adult Nova Scotia Duck Tolling Retrievers.


Congenital Ichthyosis 2 in the Golden Retriever - A skin condition in which the outer layer of the skin does not form properly and results in scaling. The condition often progresses to large patches of thickened, black, scaly skin. Two genetic variants have been associated with congenital ichthyosis in the Golden Retriever.

Junctional Epidermolysis Bullosa in the Saddlebred (JEB2) - An inherited disease that causes moderate to severe blistering of the skin and mouth epithelia, sloughing of hooves in newborn foals, and skin lesions that develop as the foal ages. This test detects a causal variant specific to Saddlebreds and related breeds.

Multidrug sensitivity (MDR1) - Dogs with multidrug sensitivity are predisposed to adverse reactions (neurotoxicity) following use of certain common drugs, like ivermectin, which is found in heartworm medication.


Shedding+ - The extent of shedding is impacted by several genes, but combinations of variants in the MC5R and RSPO2 genes in particular result in decreased overall shedding rates.

APRIL 2022

Lhasa Apso Albinism (French Bulldog Pink) - a phenotype caused by a missense variant in the SLC45A2 gene where affected dogs display white fur and pink skin, as well as pink nose, lips and paw pads. Research at the VGL has identified this same variant in French Bulldogs with a coat color commonly referred to as pink in the breed. 

Updated French Bulldog Coat Color Panel - Our coat color panel specifically tailored for French Bulldogs has been updated to include Brown and Cocoa. The updated coat color panel now tests for Agouti (A Locus), Brown (B Locus/Chocolate/Liver), Cocoa, Dilute (D Locus/Blue), Dominant Black (K Locus), MC1R (E Locus), and Piebald/White Spotting (S Locus).



New Agouti - a new agouti test has been developed for dogs based on research by UC Davis Professor Dr. Danika Bannasch and colleagues. The new test looks at two separate regions of the A locus that regulate the amount of expression of the Agouti protein and is able to differentiate between phenotypes that were previously indistinguishable. The new Agouti test better explains the coat pattern variation in dogs, providing breeders with a more accurate phenotype-genotype correlation!