Variants in the PMEL17 gene (aka SILV) cause a color dilution from red or black to pale cream or white coat color. This gene has a dosage-dependent effect on pigment, with a single allele diluting black to gray and red to pale red, and a double dose producing a significantly lighter coat.
This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents. The markers reported include the 12 ISAG-recommended markers for cattle. Genotypes follow the international nomenclature standard for cattle.
Progressive ataxia (PA) of Charolais cattle is an inherited neurodegenerative disease affecting the hind limbs that can gradually progress until the affected animal is unable to stand.
The Melanocortin 1 Receptor (MC1R) gene (also called Extension) controls the production of black and red pigments in the coats of domestic cattle, creating base colors that may then be further modified by other genes.
A freemartin is a female that is born as a twin with a male and is sterile as a result of exposure to masculinizing hormones produced by the male in utero.
Polled cattle breeds have been selectively bred to lack horns. Polledness is a dominant trait: all offspring of a bull with 2 copies of a polled-associated mutation will be polled themselves.
