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Collie Eye Anomaly (CEA), also known as choroidal hypoplasia, is a heritable disorder that can result in abnormal development of inner structures of the eye. This genetic variant is associated with CEA in multiple breeds.
Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progressive vision loss leading to total blindness. This Shetland Sheepdog type PRA is caused by a mutation in the CNGA1 gene. This is not the only cause of PRA in the breed.
Rod-cone dysplasia type 2 (rcd2) is a type of early-onset retinal degeneration that affects collie breeds and typically lead to blindness.
Dermatomyositis (DMS) is an immune-mediated disorder that affects skin and muscle in the Collie and Shetland Sheepdog.
Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progressive vision loss leading to total blindness. A deletion in the CACNA1F gene is one cause of PRA in racing Greyhounds. There are many known genetic causes for PRA in dogs.
The Agouti Signaling Protein (ASIP) gene interacts with the MC1R gene to control red (phaeomelanin) ...
Alaskan Husky encephalopathy is an inherited fatal neurological disorder characterized by seizures, ...
Alaskan Malamute polyneuropathy is an inherited neuromuscular defect of varying severity most often ...
Adverse owner-reported behaviors (such as seizure, “glazing over”, episodic biting, and general loss...
The Brown gene dilutes eumelanin (black pigment) to brown but does not affect phaeomelanin (red/yell...
The Veterinary Genetics Laboratory (VGL), in collaboration with Dr. Niels C. Pedersen and staff, has...
Canine leukocyte adhesion deficiency, Type III (CLAD-Type III) is an inherited blood disorder affect...
Canine leukocyte adhesion deficiency, Type I (CLAD-Type I) is an inherited blood disorder affecting ...
Canine multifocal retinopathy 1 is an inherited eye disease characterized by areas of retinal detach...
Canine multifocal retinopathy 2 is an inherited eye disease characterized by areas of retinal detach...
Canine multifocal retinopathy 3 is an inherited eye disease characterized by areas of retinal detach...
Cardiac Laminopathy (CLAM) is a fatal heritable condition that results in dilated cardiomyopathy and...
Centronuclear myopathy is a hereditary myopathy of Labrador Retrievers characterized by generalized ...
Spinocerebellar ataxia (also known as cerebellar ataxia or CA) is an inherited disorder that affects...
Cerebellar Degeneration-Myositis Complex (CDMC) is a heritable disorder that causes neurological sig...
Chondrodysplasia is a short-legged phenotype characteristic of many dog breeds. Chondrodystrophy, a ...
Chondrodystrophy, a trait that is characterized by a short-legged phenotype, also impacts the health...
The CLPS genetic variant causes development of cleft palate and/or cleft lip, sometimes also accompa...
There are multiple genetic causes of cleft palate within the Nova Scotia Duck Tolling Retriever bree...
Five recessive variants in the fibroblast growth factor-5 (FGF5) gene are associated with long hair ...
A brown coat color resulting in a slightly darker coat than the brown color caused by other variants...
Collie Eye Anomaly (CEA), also known as choroidal hypoplasia, is a heritable disorder that can resul...
Loss of cone function due to cone degeneration results in day-blindness and decreased visual acuity....
Cone Rod Dystrophy 1 and 2 cause early onset retinal degeneration leading to blindness in the Americ...
Congenital ichthyosis is a skin condition in which the outer layer of the skin does not form properl...
Congenital ichthyosis is a skin condition in which the outer layer of the skin does not form properl...
Congenital myasthenic syndrome is a group of inherited neuromuscular disorders that are characterize...
Congenital myasthenic syndrome (CMS) is a neuromuscular disorder in Labrador Retrievers characterize...
Copper toxicosis is a metabolic disorder that can cause chronic liver failure and neurological probl...
Two variants in the Keratin-71 gene are associated with curly hair in dogs. Dogs with these curl var...
Cyclic neutropenia, also known as Gray Collie Syndrome, is a heritable disorder that affects Collies...
Cystinuria type I-A is a kidney disorder in which the kidneys are unable to reabsorb cystine, leadin...
In Doberman Pinschers, a neurological disorder causing deafness and balance/coordination issues, com...
Degenerative myelopathy (DM) is an inherited neurologic disorder of dogs characterized by gradual mu...
Dilated cardiomyopathy is a condition in which the heart has a decreased ability to pump blood. Two ...
Several gene variants are known to produce dilute coloration in dogs. Colors are lightened (diluted)...
The Dominant Black gene (K Locus) affects pigment switching between eumelanin (black) and phaeomelan...
Exercise-induced collapse is a genetic neuromuscular disorder characterized by muscle weakness, lack...
Factor VII deficiency is a mild to moderate inherited blood clotting disorder. Affected dogs may app...
Autosomal recessive amelogenesis imperfecta (ARAI), also known as familial enamel hypoplasia (FEH), ...
Autosomal recessive amelogenesis imperfecta (ARAI), also known as familial enamel hypoplasia (FEH), ...
Fanconi syndrome is a heritable kidney disorder that affects Basenjis. Affected dogs typically prese...
A dominant variant of the R-spondin-2 gene produces the longer mustache and eyebrows seen in wire-ha...
GM1 gangliosidosis in the Shiba Inu breed (SI-GM1) is a progressive, lethal disorder caused by abnor...
GM2 gangliosidosis is a fatal neurodegenerative lysosomal storage disease that affects dogs. This GM...
The American Hairless Terrier is a breed that includes hairless and coated varieties. The breed's ch...
Harlequin is a pattern seen in Great Danes resulting from the complex interaction of the Merle and H...
Hemophilia A/Factor VIII Deficiency is an inherited bleeding disorder in Boxers caused by a deficien...
Hemophilia A/Factor VIII Deficiency is an inherited bleeding disorder in German Shepherd Dogs and re...
Cataracts (clouding of the lens of the eye) are a common cause of blindness in dogs. In Australian S...
Hereditary nasal parakeratosis is an inherited, recessive genetic defect that affects specialized ce...
Hyperuricosuria is an inherited disorder characterized by elevated levels of uric acid in the urine ...
Hypomyelination in Weimaraners leads to tremors during puppyhood that often resolve by 3-4 months of...
Imerslund-Gräsbeck syndrome (IGS) is a disorder found in Beagles and Border Collies where vitamin B1...
Inherited myopathy of Great Danes (IMGD) is a rapidly progressive muscle myopathy characterized by e...
The intensity coat color gene variant causes an extreme dilution of phaeomelanin (red or yellow pigm...
Addison’s disease occurs when the adrenal glands stop secreting necessary natural steroid hormones. ...
Juvenile hereditary cataracts are an inherited form of cataracts that commonly cause blindness in do...
Leukoencephalomyelopathy is a neurodegenerative disorder of the central nervous system characterized...
Lhasa Apso Albinism (LAA) is an oculocutaneous albinism that is characterized by white or off-white ...
The melanocortin 1 receptor (MC1R) gene controls production of the pigments eumelanin (black) and ph...
Merle is an incompletely dominant coat color pattern characterized by irregularly shaped patches of ...
Mucopolysaccharidosis VII (MPS VII) is a lysosomal storage disease characterized by skeletal abnorma...
Mucopolysaccharidosis VII (MPS VII) is a lysosomal storage disease characterized by skeletal abnorma...
Multidrug Sensitivity is caused by a deletion in the ABCB1 gene, also known as the multidrug resista...
Musladin-Lueke Syndrome (MLS) is a genetic disease in Beagles that affects the development and struc...
Narcolepsy is a disorder of the nervous system characterized by periods of sleepiness. This test det...
Narcolepsy in Labrador Retrievers is a sleeping disorder characterized by daytime sleepiness, fragme...
Natural bobtail is a naturally occurring mutation in the T-box transcription factor T gene resulting...
Neonatal cerebellar cortical degeneration in young Beagle puppies is characterized by lack of coordi...
Neonatal encephalopathy with seizures is an inherited progressive brain disease of Standard Poodles ...
Neuroaxonal dystrophy (NAD) in Rottweiler dogs is a degenerative neurological disease characterized ...
Neuronal ceroid lipofuscinosis results from the accumulation of granules in the neurons of the brain...
“White” (cream-colored) Doberman Pinschers display a color dilution of the coat, eyes, and skin caus...
Osteochondrodysplasia is characterized by stunted growth and abnormal locomotion. Affected animals d...
Osteogenesis imperfecta is an inherited disease which causes defective collagen, leading to extremel...
A mutation in the KIT gene has been found to be the source of the dominant white spotting pattern kn...
This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an o...
White spotting patterns that occur in many dog breeds do not have a uniform genetic basis, and the g...
Previously described as juvenile-onset, laryngeal paralysis and polyneuropathy (JLPP), polyneuropath...
Primary lens luxation is a painful inherited eye disorder where the lens of the eye moves from its n...
This inherited primary open angle glaucoma in Beagles results from a mutation in the gene ADAMTS10. ...
Primary open-angle glaucoma (POAG) is a type of glaucoma that typically progresses gradually without...
Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progre...
Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progre...
Progressive retinal atrophy (PRA) is characterized by bilateral degeneration of the retina resulting...
Progressive retinal atrophy (PRA) in the Sloughi is a late onset inherited rod-cone dysplasia that l...
Progressive retinal atrophy rod-cone degeneration 4 (rcd4-PRA) is a heritable condition characterize...
Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progre...
Progressive rod-cone degeneration (PRCD) is an inherited form of late-onset progressive retinal atro...
Pyruvate kinase deficiency (PKDef) is an inherited hemolytic anemia caused by a defect in the enzyme...
Pyruvate kinase deficiency in Labrador Retrievers is a chronic, severe hemolytic anemia caused by de...
Pyruvate kinase deficiency in the Basenji is a chronic, severe hemolytic anemia caused by defective ...
Renal cystadenocarcinoma and nodular dermatofibrosis is an inherited cancer in German Shepherd Dogs.
Rod-cone dysplasia type 2 (rcd2) is a type of early-onset retinal degeneration that affects collie b...
Saluki encephalopathy is a neurological disorder caused by Succinic Semialdehyde Dehydrogenase Defic...
Sensory ataxic neuropathy is a progressive neurological disorder characterized by involuntary muscle...
The extent of shedding is impacted by several genes but two, MC5R and RSPO2, appear to have signific...
Skeletal dysplasia 2 (SD2) is an inherited disorder that causes a mild form of disproportionate dwar...
Spinal dysraphism (SD) in Weimaraner dogs is a genetic disorder present at birth that results from f...
Stargardt disease is a degenerative eye disorder resulting from the progressive loss of the photorec...
Dermatomyositis (DMS) is an immune-mediated disorder that affects skin and muscle in the Collie and ...
Primary closed angle glaucoma (PCAG) is a hereditary disease that results from a rapid build-up of p...
Progressive retinal atrophy (PRA) is a genetic disease characterized by progressive photoreceptor de...
Necrotizing meningoencephalitis (NME), also known as Pug dog encephalitis, is an inflammatory diseas...
Trapped neutrophil syndrome is an inherited neutropenia in Border Collies that compromises the immun...
Von Willebrand disease I (vWD Type 1), an inherited bleeding disorder, results from a lack or reduce...
Von Willebrand disease II (vWD Type 2), an inherited bleeding disorder, results from a lack or reduc...
Von Willebrand disease III (vWD Type 3), an inherited bleeding disorder, results from a lack or redu...
X-linked hypohidrotic ectodermal dysplasia is an inherited disorder that affects tissues derived fro...
X-linked myotubular myopathy in Labrador Retrievers is an inherited muscle disease that manifests wi...
X-linked myotubular myopathy in Rottweilers is an inherited muscle disease that manifests with sever...
Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progre...