Cystinuria type I-A is a kidney disorder in which the kidneys are unable to reabsorb cystine, leading to the formation of crystals in the urinary tract, which can cause urinary obstruction, difficulty in passing urine, and presence of blood in the urine.
Degenerative myelopathy (DM) is an inherited neurologic disorder of dogs characterized by gradual muscle wasting and loss of coordination typically beginning in the hind limbs. Testing is most appropriate for those breeds in which the clinical disease has been associated with the SOD1 allele.
Exercise-induced collapse is a genetic neuromuscular disorder characterized by muscle weakness, lack of coordination, and life-threatening collapse after intense exercise in otherwise apparently healthy dogs.
Hereditary nasal parakeratosis is an inherited, recessive genetic defect that affects specialized cells of the canine nose, resulting in the formation of a crust with cracks over the nasal area of young dogs.
Narcolepsy in Labrador Retrievers is a sleeping disorder characterized by daytime sleepiness, fragmented sleep patterns, and sudden transient episodes of muscle weakness or paralysis triggered by play or food. This test detects a causal variant specific to Labrador Retrievers.
Pyruvate kinase deficiency in Labrador Retrievers is a chronic, severe hemolytic anemia caused by defective production of the enzyme pyruvate kinase. Signs in affected dogs may include lethargy, low exercise tolerance, and fatigue.
Stargardt disease is a degenerative eye disorder resulting from the progressive loss of the photoreceptor cells that are responsible for sensing light. Affected dogs show a decline in vision with age but appear to retain some vision throughout their life.