Collie Eye Anomaly (CEA), also known as choroidal hypoplasia, is a heritable disorder that can result in abnormal development of inner structures of the eye. This genetic variant is associated with CEA in multiple breeds.
Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progressive vision loss leading to total blindness. This Shetland Sheepdog type PRA is caused by a mutation in the CNGA1 gene. This is not the only cause of PRA in the breed.
Cyclic neutropenia, also known as Gray Collie Syndrome, is a heritable disorder that affects Collies. The condition causes episodes of low neutrophil counts, resulting in recurrent infections, stunted growth and shortened life span.
Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progressive vision loss leading to total blindness. This Basenji PRA is caused by a mutation in the S-antigen (SAG) gene.
Pyruvate kinase deficiency in the Basenji is a chronic, severe hemolytic anemia caused by defective production of the enzyme pyruvate kinase. Signs in affected dogs may include lethargy, low exercise tolerance, and fatigue.