Congenital myotonia, characteristic of Fainting Goats, is a heritable neuromuscular disorder characterized by a slow relaxation of skeletal muscles following voluntary contraction. The sudden muscle stiffness often causes the animal to fall over briefly.
Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progressive vision loss leading to total blindness. A deletion in the CACNA1F gene is one cause of PRA in racing Greyhounds. There are many known genetic causes for PRA in dogs.
Collie Eye Anomaly (CEA), also known as choroidal hypoplasia, is a heritable disorder that can result in abnormal development of inner structures of the eye. This genetic variant is associated with CEA in multiple breeds.
Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progressive vision loss leading to total blindness. This Shetland Sheepdog type PRA is caused by a mutation in the CNGA1 gene. This is not the only cause of PRA in the breed.
Cyclic neutropenia, also known as Gray Collie Syndrome, is a heritable disorder that affects Collies. The condition causes episodes of low neutrophil counts, resulting in recurrent infections, stunted growth and shortened life span.
