Lhasa Apso Albinism (LAA) is characterized by white fur and pink skin, and is caused by a missense variant in the SLC45A2 gene. This variant is also responsible for French Bulldog Pink.
Congenital ichthyosis is a skin condition in which the outer layer of the skin does not form properly and results in scaling. The condition often progresses to large patches of thickened, black, scaly skin.
Congenital myasthenic syndrome is a group of inherited neuromuscular disorders that are characterized by progressive muscle weakening that worsens with exercise.
Neuronal ceroid lipofuscinosis results from the accumulation of granules in the neurons of the brain and spinal cord. This progressive neurological disorder manifests as behavioral changes coupled with a loss of coordination and blindness.
Sensory ataxic neuropathy is a progressive neurological disorder characterized by involuntary muscle movements and abnormal posture resulting from degeneration of the nerves controlling muscle movement. It affects both sexes but is only inherited maternally.
In Doberman Pinschers, a neurological disorder causing deafness and balance/coordination issues, commonly referred to as DINGS, is associated with variants in two different genes. One appears to result in deafness in one ear while the other shows deafness in both ears.
A brown coat color resulting in a slightly darker coat than the brown color caused by other variants. This color is seen in French Bulldogs and was previously referred to as “non-testable chocolate”.
Stargardt disease is a degenerative eye disorder resulting from the progressive loss of the photoreceptor cells that are responsible for sensing light. Affected dogs show a decline in vision with age but appear to retain some vision throughout their life.
