Copper toxicosis is a metabolic disorder that can cause chronic liver failure and neurological problems that result from deviations in normal levels of copper in the body. This test identifies genetic variants associated with risk for copper toxicosis or copper deficiency in the Labrador Retriever, Doberman Pinscher, Black Russian Terrier and Bedlington Terrier.
Progressive rod-cone degeneration (PRCD) is an inherited form of late-onset progressive retinal atrophy (PRA) that has been identified in many dog breeds.
A variant in the Keratin-71 gene is associated with curly hair in dogs. Dogs with this curl variant have curly coats or wavy coats depending on how many copies of the variant they possess.
White spotting patterns that occur in many dog breeds do not have a uniform genetic basis, and the genetics are complex. In piebald/parti/random white spotting, the extent of white pattern expression varies, and markings are often asymmetrical.