A variant in the Keratin-71 gene is associated with curly hair in dogs. Dogs with the curl variant have curly coats or wavy coats depending on how many copies of the variant they possess.
Phenotype: Dogs with the curl variant have curly coats or wavy coats depending on how many copies of the variant they possess.
Mode of Inheritance: Incomplete dominance
Alleles: N = No curl, C = Curl
Breeds appropriate for testing: Many breeds including Airedale Terrier, American Water Spaniel, Australian Labradoodle, Bichon Frise, Boykin Spaniel, Chesapeake Bay Retriever, Dachshund, Fox Terrier (Wire-haired), Goldendoodle, Havanese, Irish Water Spaniel, Kerry Blue Terrier, Kuvasz, Labradoodle, Maltese, Poodle, Portuguese Water Dog, Soft Coated Wheaten Terrier, Welsh Terrier, and Crossbreeds
Explanation of Results:
Dogs with N/N genotype are expected to have a straight coat. They cannot transmit this curl variant to their offspring.
Dogs with N/C genotype are expected to have a wavy coat. They may transmit this curl variant to 50% of their offspring. Matings between two N/C dogs are expected to produce 50% puppies with wavy hair and 25% puppies with curly hair.
Dogs with C/C genotype are expected to have a curly coat. They will transmit this curl variant to all of their offspring.
$45 one test per animal
$65 two tests for coat color/fur type/bobtail (same animal)
$85 three tests for coat color/fur type/bobtail (same animal)
+ $15 each additional test if ordering more than three coat color/fur type/bobtail tests on the same animal
Promotional pricing until August 31, 2020: $115 per animal
Additional coat colors $15 per test
A variant in the Keratin-71 (KRT71) gene is associated with curly hair in dogs. This variant is likely inherited as an incomplete dominant trait, which means that dogs with two copies of the variant (C/C) have curly coats and dogs with one copy of the variant (N/C) are not curly but have wavy coats.
This test assays the p.Arg151Trp variant in KRT71.
Cadieu, E., Neff, M.W., Quignon, P., Walsh, K., Chase, K., Parker, H.G., Vonholdt, B.M., Rhue, A., Boyko, A., Byers, A., Wong, A., Mosher, D.S., Elkahloun, A.G., Spady, T.C., André, C., Lark, K.G., Cargill, M., Bustamante, C.D., Wayne, R.K., & Ostrander, E.A. (2009). Coat variation in the domestic dog is governed by variants in three genes. Science, 326, 150-153. doi: 10.1126/science.1177808