Great Dane

Intensity Dilution

The intensity coat color gene variant causes an extreme dilution of phaeomelanin (red or yellow pigment), resulting in a cream to white coat in dogs.

Parentage/Genetic Marker Report

This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents.

Canine Genetic Diversity

The Veterinary Genetics Laboratory (VGL), in collaboration with Dr. Niels C. Pedersen and staff, has developed a panel of short tandem repeat (STR) markers that will determine genetic diversity across the genome and in the Dog Leukocyte Antigen (DLA) class I and II regions. This test panel is useful to breeders who wish to track and increase genetic diversity of their breed as a long term goal. Please note, this test will not identify breed.

Dog Coat Color - Great Dane Panel

Group of colorful Great Dane puppies

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This panel of coat color tests is specifically tailored to the Great Dane breed.

Furnishings and Improper Coat

A dominant variant of the R-spondin-2 gene produces the longer mustache and eyebrows seen in wire-haired dogs and other breeds.

Curl

A variant in the Keratin-71 gene is associated with curly hair in dogs. Dogs with the curl variant have curly coats or wavy coats depending on how many copies of the variant they possess.

Coat Length

Five recessive variants in the fibroblast growth factor-5 (FGF5) gene are associated with long hair phenotypes in dogs.

Piebald/White Spotting (S Locus)

White spotting patterns that occur in many dog breeds do not have a uniform genetic basis, and the genetics are complex. In piebald/parti/random white spotting, the extent of white pattern expression varies, and markings are often asymmetrical.

Merle

Merle is an incompletely dominant coat color pattern characterized by irregularly shaped patches of diluted pigment and solid color.