Basenji

Fanconi syndrome is a heritable kidney disorder that affects Basenjis. Affected dogs typically present kidney dysfunction around 4-8 years of age.

Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progressive vision loss leading to total blindness. This Basenji PRA is caused by a mutation in the S-antigen (SAG) gene.

Pyruvate kinase deficiency in the Basenji is a chronic, severe hemolytic anemia caused by defective production of the enzyme pyruvate kinase. Signs in affected dogs may include lethargy, low exercise tolerance, and fatigue.

The intensity coat color gene variant causes an extreme dilution of phaeomelanin (red or yellow pigment), resulting in a cream to white coat in dogs.

This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents.

A dominant variant of the R-spondin-2 gene produces the longer mustache and eyebrows seen in wire-haired dogs and other breeds.

Two variants in the Keratin-71 gene are associated with curly hair in dogs. Dogs with these curl variants have curly coats or wavy coats depending on how many copies of the allele they possess.

Five recessive variants in the fibroblast growth factor-5 (FGF5) gene are associated with long hair phenotypes in dogs.