Primary open-angle glaucoma (POAG) is a type of glaucoma that typically progresses gradually without obvious signs of pain. A genetic inversion disrupting the ADAMTS17 gene is associated with POAG in the Petit Basset Griffon Vendeen, which is characterized by elevated intraocular pressure and lens subluxation, and can lead to vision loss at a later stage of the disease.
Progressive rod-cone degeneration (PRCD) is an inherited form of late-onset progressive retinal atrophy (PRA) that has been identified in many dog breeds.
Two variants in the Keratin-71 gene are associated with curly hair in dogs. Dogs with these curl variants have curly coats or wavy coats depending on how many copies of the allele they possess.
White spotting patterns that occur in many dog breeds do not have a uniform genetic basis, and the genetics are complex. In piebald/parti/random white spotting, the extent of white pattern expression varies, and markings are often asymmetrical.