Multidrug Sensitivity is caused by a deletion in the ABCB1 gene, also known as the multidrug resistance 1 (MDR1) gene, and is characterized by neurotoxicity following the use of certain common drugs.
Progressive rod-cone degeneration (PRCD) is an inherited form of late-onset progressive retinal atrophy (PRA) that has been identified in many dog breeds.
A variant in the Keratin-71 gene is associated with curly hair in dogs. Dogs with the curl variant have curly coats or wavy coats depending on how many copies of the variant they possess.
White spotting patterns that occur in many dog breeds do not have a uniform genetic basis, and the genetics are complex. In piebald/parti/random white spotting, the extent of white pattern expression varies, and markings are often asymmetrical.