Irish Setter

Progressive retinal atrophy rod-cone degeneration 4 (rcd4-PRA) is a heritable condition characterized by late-onset degeneration of photoreceptor cells in the retina, leading to loss of vision and blindness.

The intensity coat color gene variant causes an extreme dilution of phaeomelanin (red or yellow pigment), resulting in a cream to white coat in dogs.

This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents.

The Veterinary Genetics Laboratory (VGL), in collaboration with Dr. Niels C. Pedersen and staff, has developed a panel of short tandem repeat (STR) markers that will determine genetic diversity across the genome and in the Dog Leukocyte Antigen (DLA) class I and II regions. This test panel is useful to breeders who wish to track and increase genetic diversity of their breed as a long term goal. Please note, this test will not identify breed.

Progressive rod-cone degeneration (PRCD) is an inherited form of late-onset progressive retinal atrophy (PRA) that has been identified in many dog breeds.

A dominant variant of the R-spondin-2 gene produces the longer mustache and eyebrows seen in wire-haired dogs and other breeds.

Two variants in the Keratin-71 gene are associated with curly hair in dogs. Dogs with these curl variants have curly coats or wavy coats depending on how many copies of the allele they possess.

Five recessive variants in the fibroblast growth factor-5 (FGF5) gene are associated with long hair phenotypes in dogs.

White spotting patterns that occur in many dog breeds do not have a uniform genetic basis, and the genetics are complex. In piebald/parti/random white spotting, the extent of white pattern expression varies, and markings are often asymmetrical.