Labradoodle

Congenital Ichthyosis in Labrador Retrievers

Congenital ichthyosis is a skin condition in which the outer layer of the skin does not form properly and results in scaling. The condition often progresses to large patches of thickened, black, scaly skin. A recently identified allele is associated with congenital ichthyosis in the Labrador Retriever and is referred to as congenital ichthyosis type 3 (ICH3).

Copper Toxicosis (Menkes and Wilson diseases)

Copper toxicosis is a metabolic disorder that can cause chronic liver failure and neurological problems that result from deviations in normal levels of copper in the body. This test identifies genetic variants associated with risk for copper toxicosis or copper deficiency in the Labrador Retriever, Doberman Pinscher, Black Russian Terrier and Bedlington Terrier.

Intensity Dilution

The intensity coat color gene variant causes an extreme dilution of phaeomelanin (red or yellow pigment), resulting in a cream to white coat in dogs.

Parentage/Genetic Marker Report

This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents.

Pyruvate Kinase Deficiency (PKDef) in Labrador Retrievers

Pyruvate kinase deficiency in Labrador Retrievers is a chronic, severe hemolytic anemia caused by defective production of the enzyme pyruvate kinase. Signs in affected dogs may include lethargy, low exercise tolerance, and fatigue.

Furnishings and Improper Coat

A dominant variant of the R-spondin-2 gene produces the longer mustache and eyebrows seen in wire-haired dogs and other breeds.

Curl

A variant in the Keratin-71 gene is associated with curly hair in dogs. Dogs with the curl variant have curly coats or wavy coats depending on how many copies of the variant they possess.