Labradoodle

Congenital ichthyosis is a skin condition in which the outer layer of the skin does not form properly and results in scaling. The condition often progresses to large patches of thickened, black, scaly skin. A recently identified allele is associated with congenital ichthyosis in the Labrador Retriever and is referred to as congenital ichthyosis type 3 (ICH3).

Copper toxicosis is a metabolic disorder that can cause chronic liver failure and neurological problems that result from deviations in normal levels of copper in the body. This test identifies genetic variants associated with risk for copper toxicosis or copper deficiency in the Labrador Retriever, Doberman Pinscher, Black Russian Terrier and Bedlington Terrier.

The intensity coat color gene variant causes an extreme dilution of phaeomelanin (red or yellow pigment), resulting in a cream to white coat in dogs.

This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents.

Progressive rod-cone degeneration (PRCD) is an inherited form of late-onset progressive retinal atrophy (PRA) that has been identified in many dog breeds.

Pyruvate kinase deficiency in Labrador Retrievers is a chronic, severe hemolytic anemia caused by defective production of the enzyme pyruvate kinase. Signs in affected dogs may include lethargy, low exercise tolerance, and fatigue.

A dominant variant of the R-spondin-2 gene produces the longer mustache and eyebrows seen in wire-haired dogs and other breeds.

Two variants in the Keratin-71 gene are associated with curly hair in dogs. Dogs with these curl variants have curly coats or wavy coats depending on how many copies of the allele they possess.

Skeletal dysplasia 2 (SD2) is an inherited disorder that causes a mild form of disproportionate dwarfism consisting of short legs with normal body length and width.