Collie

Dermatomyositis (DMS) is an immune-mediated disorder that affects skin and muscle in the Collie and Shetland Sheepdog.

Collie Eye Anomaly (CEA), also known as choroidal hypoplasia, is a heritable disorder that can result in abnormal development of inner structures of the eye. This genetic variant is associated with CEA in multiple breeds.

Cyclic neutropenia, also known as Gray Collie Syndrome, is a heritable disorder that affects Collies. The condition causes episodes of low neutrophil counts, resulting in recurrent infections, stunted growth and shortened life span.

Rod-cone dysplasia type 2 (rcd2) is a type of early-onset retinal degeneration that affects collie breeds and typically lead to blindness.

Multidrug Sensitivity is caused by a deletion in the ABCB1 gene, also known as the multidrug resistance 1 (MDR1) gene, and is characterized by neurotoxicity following the use of certain common drugs. Dogs with two copies of MDR1 will exhibit multidrug sensitivity. Some dogs with 1 copy of MDR1 may also exhibit multidrug sensitivity.

The intensity coat color gene variant causes an extreme dilution of phaeomelanin (red or yellow pigment), resulting in a cream to white coat in dogs.

This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents.

The Veterinary Genetics Laboratory (VGL), in collaboration with Dr. Niels C. Pedersen and staff, has developed a panel of short tandem repeat (STR) markers that will determine genetic diversity across the genome and in the Dog Leukocyte Antigen (DLA) class I and II regions. This test panel is useful to breeders who wish to track and increase genetic diversity of their breed as a long term goal. Please note, this test will not identify breed.

Progressive rod-cone degeneration (PRCD) is an inherited form of late-onset progressive retinal atrophy (PRA) that has been identified in many dog breeds.