Dog

Dog
Breed

Neuronal Ceroid Lipofuscinosis (NCL) in Golden Retrievers

Neuronal ceroid lipofuscinosis results from the accumulation of granules in the neurons of the brain and spinal cord. This progressive neurological disorder manifests as behavioral changes coupled with a loss of coordination and blindness.

Sensory Ataxic Neuropathy (SAN) in Golden Retrievers

Sensory ataxic neuropathy is a progressive neurological disorder characterized by involuntary muscle movements and abnormal posture resulting from degeneration of the nerves controlling muscle movement. It affects both sexes but is only inherited maternally.

Deafness with Vestibular Dysfunction (DVD), aka DINGS

In Doberman Pinschers, a neurological disorder causing deafness and balance/coordination issues, commonly referred to as DINGS, is associated with variants in two different genes. One appears to result in deafness in one ear while the other shows deafness in both ears.

Cocoa

A brown coat color resulting in a slightly darker coat than the brown color caused by other variants. This color is seen in French Bulldogs and was previously referred to as “non-testable chocolate”.

Stargardt Disease in Labrador Retrievers

Stargardt disease is a degenerative eye disorder resulting from the progressive loss of the photoreceptor cells that are responsible for sensing light. Affected dogs show a decline in vision with age but appear to retain some vision throughout their life.

Copper Toxicosis (Menkes and Wilson diseases)

Copper toxicosis is a metabolic disorder that can cause chronic liver failure and neurological problems that result from deviations in normal levels of copper in the body. This test identifies genetic variants associated with risk for copper toxicosis or copper deficiency in the Labrador Retriever, Doberman Pinscher, Black Russian Terrier and Bedlington Terrier.

Dilated Cardiomyopathy 1 and 2 in Doberman Pinschers

Dilated cardiomyopathy is a condition in which the heart has a decreased ability to pump blood. Two mutations associated with dilated cardiomyopathy in Doberman Pinschers have been identified. Testing for these mutations can identify individuals at risk for developing clinical symptoms of disease.