Necrotizing meningoencephalitis (NME), also known as Pug dog encephalitis, is an inflammatory disease of the central nervous system that is usually progressive and fatal. Several genetic markers are associated with risk of developing NME.
Addison’s disease occurs when the adrenal glands stop secreting necessary natural steroid hormones. In the Nova Scotia Duck Tolling Retriever, a genetic form of Addison's disease can occur in puppies.
There are multiple genetic causes of cleft palate within the Nova Scotia Duck Tolling Retriever breed. The most common form has been identified as CP1.
The CLPS genetic variant causes development of cleft palate and/or cleft lip, sometimes also accompanied by syndactly (fused toes), in Nova Scotia Duck Tolling Retriever puppies.
Progressive retinal atrophy (PRA) is a genetic disease characterized by progressive photoreceptor degeneration that leads to blindness. Mutations in 5 loci are associated with susceptibility to 90% of the PRA in Italian Greyhounds.
Primary closed angle glaucoma (PCAG) is a hereditary disease that results from a rapid build-up of pressure in the eye; if left untreated it will lead to blindness.