This inherited primary open angle glaucoma in Beagles results from a mutation in the gene ADAMTS10. The condition is characterized by increased pressure in the eye; nerve damage, vision loss, lens subluxation, and blindness may result.
Neonatal cerebellar cortical degeneration in young Beagle puppies is characterized by lack of coordination, broad based stance, loss of balance, and tremors.
Musladin-Lueke Syndrome (MLS) is a genetic disease in Beagles that affects the development and structure of connective tissue across multiple organ systems.
Cone Rod Dystrophy 1 and 2 cause early onset retinal degeneration leading to blindness in the American Staffordshire Terrier and American Pit Bull Terrier.
Alaskan Malamute polyneuropathy is an inherited neuromuscular defect of varying severity most often characterized by abnormal changes in the dog's gait and mobility.
Juvenile hereditary cataracts are an inherited form of cataracts that commonly cause blindness in dogs by clouding the lens of the eye and affecting both eyes symmetrically.
Cataracts (clouding of the lens of the eye) are a common cause of blindness in dogs. In Australian Shepherds, a genetic mutation causes hereditary cataracts, which may start forming after 2 years of age and show variable rate of progression and vision impairment.
Chondrodysplasia is a short-legged phenotype characteristic of many dog breeds. Chondrodystrophy, a separate mutation, also includes a short-legged phenotype as well as premature disc degeneration and increased susceptibility to disc herniation.
