Created at the VGL Cornish Rex Coat

Quick Summary

Cornish Rex cats have short, soft, curly coats inherited in an autosomal recessive fashion. This trait is fixed in the breed.

Cornish Rex cat
Cornish Rex

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Phenotype: Cornish Rex cats have short, soft, curly coats.

Mode of Inheritance: Autosomal recessive

Alleles: N = Normal coat, CR = Cornish Rex coat

Breeds appropriate for testing: Cornish Rex

Explanation of Results:

  • Cats with N/N genotype will have normal coats and cannot transmit this Cornish Rex coat variant to their offspring.
  • Cats with N/CR genotype will have normal coats and are carriers of this Cornish Rex coat variant. Matings between two carriers are predicted to produce 25% of kittens with Cornish Rex coats.
  • Cats with CR/CR genotype will have a Cornish Rex coat and will transmit this Cornish Rex coat variant to all of their offspring. Matings with other CR/CR genotype cats are expected to produce all Cornish Rex coated kittens.

Price

$44 one test per animal

Turnaround Time
At least 15 business days; may be delayed beyond 15 business days if sample requires additional testing, or a new sample is requested.
Additional Details

Cornish Rex cat
Cornish Rex

The Cornish Rex breed of cat is characterized by a soft curly coat. The Lyons Feline Genetics Research Laboratory at University of California, Davis identified a 4 bp deletion (c.250-253 delTTTG) in lysophosphatidic acid receptor 6 (LPAR6). The mutation, inherited in an autosomal recessive fashion, affects the function of a gene crucial for hair formation and maintenance and is fixed in Cornish and also found in German Rex cats.

Testing for the Cornish Rex curly coat mutation in Cornish Rex cats can assist breeders in confirming breed affiliation as they are fixed for the variant. Test results can also be used in outcrossing programs, to help breeders select the carrier cats that could produce curly coat in the next generation.

Type of Sample
Cotton Swab

Species

Cat

Breed

Cornish Rex German Rex
Type of Test
Coat Color and/or Type
Results Reported As
Test Result Cornish Rex Coats
N/N Normal. Cat does not have Cornish Rex mutation.
N/CR

Carrier. Cat has one copy of Cornish Rex mutation. Breedings between carriers are expected to produce 25% curly coated offspring.
CR/CR

Curly coat.
References

Gandolfi, B., Alhaddad, H., Affolter, V.K., Brockman, J., Haggstrom, J., Joslin, S.E., Koehne, A.L., Mullikin, J.C., Outerbridge, C.A., Warren, W.C., Lyons, L.A. (2013). To the root of the curl: a signature of a recent selective sweep identifies a mutation that defines the Cornish Rex cat breed. PLoS One 8:e67105. doi: 10.1371/journal.pone.0067105

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