American Curl

Parentage/Genetic Marker Report

This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents.

Progressive Retinal Atrophy (PRA rdAc) (Abyssinian)

This progressive retinal atrophy is an inherited late-onset blindness condition seen in Abyssinian, Somali, and some Ocicat and other breeds. Affected cats have normal vision at birth that slowly degenerates to blindness.

Long Hair

Four mutations that produce long-haired coats in domestic cats have been identified in a single gene. Three of the mutations are fairly breed specific, while the fourth is present in all long-haired cat breeds and crossbreds.

Dilute

Dilute is an autosomal recessive trait that causes clumping and uneven distribution of pigment granules in the hair shaft, producing dilution of all coat colors.

Colorpoint Restriction

Cats with colored 'points' have genetic mutations associated with temperature-sensitive pigment production. Pigment production is reduced in warmer areas of the body, leading to darker pigmentation in the cat's cooler extremities (paws, ears, etc.)

Agouti

The agouti signaling protein interacts with the melanocortin 1 receptor to switch between black and red pigments, creating a banding pattern in individual hairs. Mutations in the agouti signaling protein gene (ASIP) prevent this switch from occurring, resulting in hairs of uniform color.

AB Blood Group in Domestic Cat Breeds

The AB system is the major blood group system in domestic cats. The common blood types are A and B, and a third rare type "AB" is also known. These blood groups are genetically determined.

Albino

The feline albino mutation is a rare mutation that produces a white coat with blue eyes, and is recessive to the sepia and Siamese mutations.