Devon Rex

Parentage/Genetic Marker Report

This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents.

Progressive Retinal Atrophy (PRA rdAc) (Abyssinian)

This progressive retinal atrophy is an inherited late-onset blindness condition seen in Abyssinian, Somali, and some Ocicat and other breeds. Affected cats have normal vision at birth that slowly degenerates to blindness.

Polycystic Kidney Disease (PKD1)

Feline polycystic kidney disease (PKD1) is a heritable form of polycystic kidney disease commonly seen in Persians and cats with Persian ancestry. Affected cats develop cysts on their kidneys, which often leads to renal failure at a later stage.

Long Hair

Four mutations that produce long-haired coats in domestic cats have been identified in a single gene. Three of the mutations are fairly breed specific, while the fourth is present in all long-haired cat breeds and crossbreds.

Dilute

Dilute is an autosomal recessive trait that causes clumping and uneven distribution of pigment granules in the hair shaft, producing dilution of all coat colors.

Colorpoint Restriction

Cats with colored 'points' have genetic mutations associated with temperature-sensitive pigment production. Pigment production is reduced in warmer areas of the body, leading to darker pigmentation in the cat's cooler extremities (paws, ears, etc.)

Cat Coat Color Panel

This panel bundles together several coat color tests that are applicable to all breeds.

Agouti

The agouti signaling protein interacts with the melanocortin 1 receptor to switch between black and red pigments, creating a banding pattern in individual hairs. Mutations in the agouti signaling protein gene (ASIP) prevent this switch from occurring, resulting in hairs of uniform color.

Sphynx and Devon Rex Coats

The Devon Rex breed produces a curly coat and the Sphynx breed is nearly hairless. The nearly hairless coat of the Sphynx breed is recessive to normal coat, and the curly coat of the Devon Rex breed is recessive to the hairless Sphynx coat.