Variants in the PMEL17 gene (aka SILV) cause a color dilution from red or black to pale cream or white coat color. This gene has a dosage-dependent effect on pigment, with a single allele diluting black to gray and red to pale red, and a double dose producing a significantly lighter coat.
This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents. The markers reported include the 12 ISAG-recommended markers for cattle. Genotypes follow the international nomenclature standard for cattle.
The Melanocortin 1 Receptor (MC1R) gene (also called Extension) controls the production of black and red pigments in the coats of domestic cattle, creating base colors that may then be further modified by other genes.
Bulldog dwarfism is a lethal genetic defect of Dexter cattle. Affected fetuses have severe disproportionate dwarfism, a short vertebral column, a large head, and are naturally aborted around seven months of gestation. The two known mutations are specific to Dexter cattle and may be present in Dexter crossbreds.
Pulmonary hypoplasia with anasarca (PHA) is a lethal genetic defect characterized by incomplete development of the lungs and severe subcutaneous fluid accumulation, leading to abortion or the birth of a dead calf.
A freemartin is a female that is born as a twin with a male and is sterile as a result of exposure to masculinizing hormones produced by the male in utero.
