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Friesian Health Panel

Friesian HorseThis health panel bundles together the three known tests for genetic diseases found in the Friesian horse.

Distichiasis

Distichiasis is a condition in which the eyelashes grow from an abnormal position on the edges of the eyelids. These misplaced lashes can contact the cornea (clear ‘window’ of the front of the eye), leading to irritation and corneal ulcers, which can impact vision.

Appaloosa Panel 1

Black and white horse with leopard spotting

A variety of coat color as well as white patterning diagnostic tests specifically for the Appaloosa and Appaloosa-related breeds.

Appaloosa Panel 2

Knabstrupper with leopard spotting

The Appaloosa Panel 2 bundles together the diagnostic tests specific to determining the presence of the leopard spotting complex.

Friesian Health Panel

Friesian HorseThis health panel bundles together the three known tests for genetic diseases found in the Friesian horse.

Horse Coat Color Panel

Herd of horses with different coat colors

Promotional Pricing Now Available - $80 for this panel!

The horse coat color panel bundles together several diagnostic tests to evaluate coat color.

Shetland Pony Coat Color Panel

Palomino Shetland PonyThe Shetland Pony Coat Color Panel bundles together several genetic tests relevant to coat color in the Shetland Pony breed.

White Pattern Panel 1

Horse with white patterning

Promotional Pricing Now Available - $40 for this panel!

The White Pattern Panel 1 offers diagnostic tests for a variety of white coat color patterns.

White Pattern Panel 2

Horse with white patterning

Promotional Pricing Now Available - $80 for this panel!

The White Pattern Panel 2 bundles together all of the white coat color/pattern diagnostic tests that the VGL offers.

Agouti (Bay/Black)

The agouti gene controls the distribution of black pigment, and determines whether a horse will have a bay or black base coat color.

Androgen Insensitivity Syndrome (AIS)

Five mutations in the androgen receptor gene, located on the X chromosome, are known to result in androgen insensitivity. Androgen insensitivity syndrome causes male horses to be sterile and appear phenotypically female.

Appaloosa Pattern-1 (PATN1)

Appaloosa Pattern-1 is a modifier of the leopard complex spotting (LP) and controls the amount of white in the coat pattern.

Camarillo White - W4

Camarillo White is a dominant white coat color characterized by a completely white coat, mane, and tail, and is found exclusively in the Camarillo White Horse.

Cerebellar Abiotrophy (CA)

Equine cerebellar abiotrophy (CA) is an inherited neurological condition found primarily in Arabian horses, and is characterized by neurological defects in foals including head tremors and ataxia.

Champagne

Champagne is a coat color dilution responsible for diluting both red and black pigment as well as causing pinkish/lavender skin and amber-colored eyes.

Cream

Cream is a dilution that causes the palomino, buckskin, smoky black, cremello, perlino, and smoky cream coat colors.

Distichiasis

Distichiasis is a condition in which the eyelashes grow from an abnormal position on the edges of the eyelids. These misplaced lashes can contact the cornea (clear ‘window’ of the front of the eye), leading to irritation and corneal ulcers, which can impact vision.

Dominant White Mutations – W5, W10, W20, and W22

Dominant white is a variable white spotting pattern caused by many different mutations in the KIT gene. The VGL tests for the four most common mutations known as W5, W10, W20, and W22. Homozygosity for W5, W10, or W22 is thought to be non-viable.

Dun Dilution

Dun is a coat color dilution characterized by lightening of the coat, with the head, lower legs, mane, and tail undiluted. Oftentimes, dun is also characterized by "primitive markings" such as a dark dorsal stripe, barring of the legs, shoulder stripes, and "cobwebbing" on the forehead.

Equine Familial Isolated Hypoparathyroidism (EFIH)

Equine familial isolated hypoparathyroidism (EFIH), previously called idiopathic hypocalcemia, is an invariably fatal condition that causes involuntary contraction of muscles and seizures due to low blood calcium concentrations in Thoroughbred foals.

Friesian Horse Dwarfism

Dwarfism in Friesians is an inherited disorder characterized by a disproportionate growth with reduced bone length of limbs and ribs while the size of the head and length of the back are normal.

Friesian Horse Hydrocephalus

Hydrocephalus is an inherited condition in Friesian and Friesian crosses characterized by excessive accumulation of fluid in the brain that results in severe cranial distension.

Gray

The gray gene causes progressive depigmentation of the hair, often resulting in a color that is almost completely white by 6-8 years of age.

Hereditary Equine Regional Dermal Asthenia (HERDA)

Hereditary equine regional dermal asthenia (HERDA) is an inherited skin condition primarily found in Quarter Horses that is characterized by hyperextensible skin, scarring, and severe lesions along the back of affected horses.

Horse Embryo Pre-Implantation Genetic Diagnosis

Pre-implantation genetic diagnosis (PGD) is a procedure used to screen embryos recovered after uterine flush to determine sex and genetic traits through DNA testing prior to implantation in the uterus.

Hyperkalemic Periodic Paralysis (HYPP)

Hyperkalemic periodic paralysis (HYPP) is an inherited disease of the muscles primarily found in Quarter Horses which is characterized by sporadic episodes of muscle tremors or paralysis.

Immune-Mediated Myositis (IMM/MYH1)

Immune-mediated myositis (IMM) is an autoimmune muscle disease that can result in severe atrophy and extreme muscle loss. The genetic susceptibility to this condition is found in quarter horses and quarter horse-related breeds.

Junctional Epidermolysis Bullosa (JEB1) in Belgians

Junctional epidermolysis bullosa (JEB) is an inherited disease that causes moderate to severe blistering of the skin and mouth epithelia, sloughing of hooves in newborn foals, and skin lesions that develop as the foal ages. This test detects a causal variant specific to Belgians and related breeds.

Lavender Foal Syndrome (LFS)

Lavender foal syndrome (LFS) is an inherited lethal coat color dilution found primarily in Arabian horses that is characterized by a dilute lavender, pale pink, or silver coat accompanied by severe neurological abnormalities.

Leopard Complex & Congenital Stationary Night Blindness

Leopard complex or appaloosa spotting is a white pattern in horses characterized by a variable amounts of white in the coat with or without pigmented leopard spots. Horses homozygous for this variant have an ocular condition known as congenital stationary night blindness.

Lethal White Overo (LWO)

Lethal white overo (LWO) is a genetic disorder that results from two copies of the version of the gene causing the frame overo coat color pattern.

Malignant Hyperthermia (MH)

Malignant hyperthermia (MH) is an inherited disease in which affected horses can be triggered by halogenated anesthetics, succinylcholine, stress, or excitement, which can induce a hyper-metabolic state characterized by symptoms including muscle contracture, elevated temperature, and an irregular heart rhythm.

Multiple Congenital Ocular Anomalies (MCOA)

Multiple congenital ocular anomalies (MCOA) is an inherited eye disorder that is associated with the silver dilution and is characterized by ocular cysts, enlargement of the cornea, abnormally formed iris/retina, and additional abnormalities.

Mushroom

Mushroom is a dilute coat color found in Shetland Ponies that results in a distinctive “sepia” toned coat, often accompanied by a flaxen mane and tail.

Naked Foal Syndrome in Akhal-Teke

Naked foal syndrome (NFS) is an inherited disorder found in the Akhal-Teke breed and is characterized by hairlessness, abnormal teeth development, digestive disorders, persistent diarrhea, and laminitis-like problems.

Occipitoatlantoaxial Malformation (OAAM)

Occipitoatlantoaxial malformation (OAAM), an inherited developmental condition primarily found in Arabian horses, causes abnormal development of the vertebrae and results in compression of the upper cervical cord with subsequent neurological damage.

Parentage/Genetic Marker Report

This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents.

Pearl

Pearl is a coat color dilution that is characterized by a dilution of the coat, mane, and tail as well as a lightening of the skin.

Polysaccharide Storage Myopathy (PSSM1)

Type 1 Polysaccharide Storage Myopathy is a glycogen storage disease that results in the accumulation of abnormal complex sugars in muscle cells, which can lead to muscle pain, weakness, and reluctance to move.

Red Factor

The extension gene, or red factor, determines whether a horse will have a chestnut base coat color or a black or bay base coat color.

Roan Zygosity Test

Roan is a white patterning coat color trait characterized by intermixed white and colored hairs in the body while the head, lower legs, mane, and tail remain colored.

Sabino 1

Sabino is a white spotting pattern that is characterized by white markings on legs often accompanied by white ticking or roaning of the midsection and a blaze on the face.

Severe Combined Immunodeficiency (SCID)

Severe combined immunodeficiency (SCID), an inherited condition primarily affecting Arabians, is characterized by an underdeveloped immune system that results in foals with elevated temperatures, respiratory stress, and diarrhea.

Silver

The silver dilution dilutes black/brown pigment to lighten the manes and tails of black and bay horses to a flaxen or silver gray. The silver dilution is also associated with an inherited ocular syndrome known as Multiple Congenital Ocular Anomalies (MCOA).

Skeletal Atavism

Skeletal atavism, an inherited bone development disorder found in Miniature Horses and Shetland Ponies, is characterized by severe angle anomalies and deformation of the front knee and hock. Affected horses typically display short legs, clubfootedness, and impaired movement.

Splashed White Mutations – SW1, SW2, SW3, SW4, SW5, and SW6

Splashed white is a variable white spotting pattern characterized by a broad blaze, extended white markings on the legs, variable white spotting on the belly, and often blue eyes. Six mutations in two different genes have been shown to cause the splashed white pattern.

SynchroGait®

SynchroGait® is a diagnostic DNA test for a genetic variant (A) that has a major impact on the gait and coordination of horses. The discovery by researchers in Sweden showed that the mutation “facilitates lateral gaits, ambling and pace, and inhibits the transition from trot or pace to gallop”. The gait A variant has been identified as a major genetic factor for performance in trotting horses and ability to perform the additional “flying pace” in Icelandic horses. 

Tiger Eye

Tiger eye is a dilute iris color characterized by a yellow, amber, or bright orange color.

Tobiano

Tobiano is a white spotting pattern characterized by white on the body that crosses the topline.

Warmblood Fragile Foal Syndrome (WFFS) Type I

Warmblood fragile foal syndrome (WFFS) type I is a recessive inherited connective tissue defect characterized by hyperextensible joints and abnormally thin fragile skin and mucous membranes.