Click here for Price and Turnaround Time
Phenotype: The albino mutation produces a white coat with blue eyes.
Mode of Inheritance: Autosomal recessive
Alleles: N = Normal/non-albino, A = Albino
Breeds appropriate for testing: Tonkinese, Siamese, blue-eyed white cats of other breeds
Explanation of Results:
- Cats with N/N genoytpe will not be albino and cannot transmit this albino variant to their offspring.
- Cats with A/N genotype will not be albino, but are carriers. They will transmit this albino variant to 50% of their offspring. Matings between two carriers are predicted to produce 25% albino kittens.
- Cats with A/A genotype will be albino, and will transmit this albino variant to all of their offspring. Matings between two A/A genotype cats are predicted to produce all albino kittens.
Feline albinism is a rare inherited condition characterized by a lack of pigment resulting in cats with a white coat and blue eyes.
Two mutations in the Tyrosinase (TYR) gene produce the Burmese (sepia), Siamese, and mink colorpoint coat and eye color phenotypes in cats. A rare mutation in TYR (c.936delC) causes a shortened form of the TYR protein and produces an albino phenotype of a white coat with blue eyes. The albino mutation is recessive to the Burmese (cb) and Siamese(cs) mutations following the allelic series C>cb=cs>ca.
|N/N||No copies of albino allele are present.|
|A/N||1 copy of the albino allele is present.|
|A/A||2 copies of the albino allele are present. Cat is albino.|
Imes, D. L., Geary, L. A., Grahn, R. A., & Lyons, L. A. (2006). Albinism in the domestic cat (Felis catus) is associated with a tyrosinase (TYR) mutation. Animal Genetics, 37(2), 175-178. doi: 10.1111/j.1365-2052.2005.01409.x