Phenotype: Champagne is a coat color dilution responsible for diluting both red and black pigment as well as causing pinkish/lavender skin and amber-colored eyes.
Mode of Inheritance:Autosomal dominant
Alleles: N = Normal or non-dilute, Ch = Champagne
Breeds appropriate for testing: Miniature Horse, Missouri Fox Trotter, Quarter Horse and related breeds, Spanish Mustang, Tennessee Walking Horse, related breeds
Explanation of Results:
Horses with N/N genotype will not be champagne dilute and cannot transmit this champagne dilution variant to their offspring.
Horses with N/Ch genotype are dilute and may transmit this champagne dilution variant to 50% of their offspring. Matings with N/N genotype will result in a 50% chance of producing a champagne dilute foal.
Horses with a chestnut base coat color and Ch/N genotype will have a gold coat often accompanied by a flaxen mane and tail.
Horses with a bay base coat color and Ch/N genotype will have tan coat accompanied by brown points.
Horses with a black base coat color and Ch/N genotype will have a dark tan coat accompanied by brown points.
Horses with Ch/Ch genotype are dilute and will pass this champagne dilution variant on to all of their offspring.
Horses with a chestnut base coat color and Ch/Ch genotype will have a gold coat often accompanied by a flaxen mane and tail.
Horses with a bay base coat color and Ch/Ch genotype will have tan coat accompanied by brown points.
Horses with a black base coat color and Ch/Ch genotype will have a dark tan coat accompanied by brown points.
At least 15 business days; may be delayed beyond 15 business days if sample requires additional testing, or a new sample is requested.
Champagne is a dominant trait that dilutes hair pigment from black to brown and red to gold. Champagne on a chestnut background (Gold) produces a gold body color and often a flaxen mane and tail that can be mistaken for palomino. Champagne on a bay background (Amber) produces a tan body color with brown points. Champagne on a black background (Classic) produces a darker tan body with brown points. The skin of Champagne-diluted horses is pinkish/lavender toned and becomes speckled with age; the speckling is particularly noticeable around the eye, muzzle, under the tail, udder, and sheath. The eye color is blue-green at birth and darkens to amber as the horse ages.
Champagne is inherited independently of other coat color genes and thus this dilution can occur in combination with any of the other genes that modify the base colors. Champagne dilution is found in Tennessee Walking Horses, Missouri Fox Trotters, Quarter Horses and related breeds, Miniature Horses and Spanish Mustangs, among others. The increasing popularity of this color is making it more common in these breeds.
A mutation in exon 2 of the Solute Carrier 36 family A1 (SLC36A1) (c.188C>G) gene causes the champagne dilution.
Testing for this champagne dilution variant can assist owners and breeders in identifying homozygous individuals (Ch/Ch) if the champagne phenotype is desired. Horses with Ch/Ch genotype will always pass on the champagne allele to their offspring and thus will consistently produce offspring with a champagne phenotype.
Cook, D., Brooks, S., Bellone, R., & Bailey, E. (2008). Missense Mutation in Exon 2 of SLC36A1 Responsible for Champagne Dilution in Horses. PLoS Genetics, 4(9):e1000195. doi: 10.1371/journal.pgen.1000195