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Dominant white is a variable white spotting pattern caused by many different mutations in the KIT gene. The VGL tests for the five most common mutations known as W5, W10, W13, W20, and W22. Homozygosity for W5, W10, W13 or W22 is thought to be non-viable.

Cream is a dilution that causes the palomino, buckskin, smoky black, cremello, perlino, and smoky cream coat colors.

The agouti gene controls the distribution of black pigment, and determines whether a horse will have a bay or black base coat color.

Degenerative myelopathy (DM) is an inherited neurologic disorder of dogs characterized by gradual muscle wasting and loss of coordination typically beginning in the hind limbs. Testing is most appropriate for those breeds in which the clinical disease has been associated with the SOD1 allele.