Cats affected by hypertrophic cardiomyopathy (HCM) are at risk of sudden cardiac death. In Ragdoll cats, a breed-specific mutation has been found to be associated with increased risk for HCM.
Cats affected by hypertrophic cardiomyopathy are at risk of sudden cardiac death. In Maine Coons, a breed-specific mutation has been found to be associated with increased risk for HCM.
Korat GM2 gangliosidosis causes progressive neurologic dysfunction and premature death in Korat cats. Disease progression is more rapid in GM2 than GM1.
Birman cats have clearly defined white feet ("gloves") as part of their breed standard. This characteristic gloving is caused by a variant in the KIT gene and is inherited as an autosomal recessive trait.
Dilute is an autosomal recessive trait that causes clumping and uneven distribution of pigment granules in the hair shaft, producing dilution of all coat colors.
Cats with colored 'points' have genetic mutations associated with temperature-sensitive pigment production. Pigment production is reduced in warmer areas of the body, leading to darker pigmentation in the cat's cooler extremities (paws, ears, etc.)
